Cissus quadrangularis is a plant native to Asia and Africa. It has been used for many medicinal purposes over time, including treatment for ulcers and hemorrhoids, due to its anti-inflammatory properties. Several studies have been done on the effects of cissus quadrangularis on weight loss. Due to some promising results from these studies, many commercial fat burners and weight loss products include cissus quadrangularis as one of the main ingredients.
Benefits
The beneficial properties of cissus quadrangularis have been studied by many researchers in India because it is a plant indigenous to that country and it has a long history of use, even showing up in ancient Ayurvedic (Sanskrit for "life knowledge") texts.
Over time cissus quadrangularis had most commonly been used for fractures and ulcers. Modern studies have shown that the plant has anti-inflammatory and analgesic properties, so its continued use was probably due to the fact that it did yield results.
One particularly promising study for weight loss was conducted in Cameroon, Africa, at the Laboratory of Nutrition and Nutritional Biochemistry at the University of Yaound. The study found that participants on 300 mg of a cissus quadrangularis supplement reduced their body mass index (BMI) by 5.4 percent, compared to no net change of BMI by participants on a placebo.
Equally important to note is that participants on cissus quadrangularis and a healthful diet plan also significantly reduced bad cholesterol levels, fasting blood glucose levels and triglyceride levels over the six-week study.
Weight Loss
Since the study done on cissus quadrangularis was published, many fat burners have included the plant extract in their formulas. However, most companies only list a "proprietary blend" on the label with the ingredients, so you don't really know how much of the extract is in a dose of the fat burner.
If you want to lose weight and enjoy the other benefits that study participants experienced, you will need to buy plain cissus quadrangularis. This way you can take two 300 mg doses a day like the study participants.
There are numerous sources of cissus quadrangularis on the market from a multitude of supplement and health food companies. The prices range from roughly $10 to over $100 per package. You will want to get a product that is a cissus quadrangularis extract without other additives or fillers. Remember that more expensive doesn't necessarily equate to a better or purer product.
For maximum weight loss and health benefits, you should couple the supplement with a sensible diet. Consult your doctor or a nutritionist to come up with a healthful, sustainable diet.
Warnings
Like many supplements, cissus quadrangularis is not recommended for women who are pregnant or breastfeeding. Other than that, the studies done found that some participants complained of headache, flatulence, dry mouth, diarrhea and insomnia. However, the number of participants in the placebo group complaining of the same symptoms was actually higher than individuals who were taking the supplement.
According to the Saunders Comprehensive Veterinary Dictionary, 3rd edition, African cissus quadrangularis contains "an unidentified toxin causing gastroenteritis"; however, there haven't been similar statements about Indian cissus quadrangularis. Also, this adverse effect is based on use in animals.
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